About I-Cell Disease


Mucolipidosis II, also known as I-Cell Disease, is a rare inherited disorder with no current treatment or cure. It occurs due to a lack of several enzymes that leads to an accumulation of fatty substances and carbohydrates within the tissues of the body. Children with I-Cell Disease typically have difficulty in walking, frequent life-threatening respiratory infections, overgrowth of gum tissue, joint stiffness, and abnormalities of the heart.


  • I-Cell disease affects approximately 2 in 1 million children worldwide.

  • Unfortunately, children with I-cell disease die in childhood, typically before the age of 10. 

  • Most affected children pass away due to respiratory failure.

  • There is no current treatment or cure for I-Cell, but the Yash Gandhi Foundation is the only foundation globally that raises and grants money solely to I-Cell research 

Phone: 484.802.2317

Address (To Mail Checks): 105 Spur Lane

West Chester, PA 19382

*for access to the "For I-Cell Families" page, please introduce yourself to us via email or other similar communication.

The Yash Gandhi Foundation is a registered 501(c)(3) not for profit organization that was founded in 2001. There are no overhead costs or salaries paid out by this foundation. All contributions are 100% directed to fund for research in I-Cell. We are the only organization worldwide that directly and solely contributes money to I-Cell research.

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